Modeling long-term tumor growth and kill after combinations of radiation and radiosensitizing agents

T. Cardilin, J. Almquist, M. Jirstrand, A. Zimmermann, F. Lignet, S. El Bawab, J. Gabrielsson. Cancer Chemotherapy and Pharmacology, Vol. 83, Issue 6, pp 1159–1173. June 2019.


Radiation therapy, whether given alone or in combination with chemical agents, is one of the cornerstones of oncology. We develop a quantitative model that describes tumor growth during and after treatment with radiation and radiosensitizing agents. The model also describes long-term treatment effects including tumor regrowth and eradication.


Photo credits: Nic McPhee